Use the bathroom before the movie - Do yourself and the rest of us a favor and use the bathroom before you sit down to enjoy the movie. If you know you can't last two hours without a visit to the bathroom, then sit at the end of the aisle, so as not to interrupt all the people you'll have to squeak by to get out.
This certainly applies to children. They say they don't need to go to the bathroom because they're excited but five to ten minutes into the movie there is a mass motion of parents and children to the exits. Take them ahead of time and get it over with (at least for the first hour of the movie anyway). There is a good reason for arriving early to a popular movie. This is one of them.